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New Product! A Letter to Our Customers Regarding CARBON60

Dr. Hank Liers, PhD new hemp CBD website integratedheathhempDear Friends,

For several years I’ve been examining the emerging research concerning what may be the world’s most powerful known antioxidant: carbon60. Carbon60 was discovered in 1985, and the three men who discovered it were awarded the Nobel Prize because it was the first new form of carbon to be discovered in roughly 300 years. Initially, it was thought that carbon60 could be used as a therapeutic agent, but this proved difficult because carbon60 is hydrophobic, meaning it repels water, so it was difficult to get it into the body.

Over the next few decades, scientists found that you could actually bind carbon60 to lipids. Once combined with a lipid or fat, the carbon60 molecule is able to penetrate the cell membrane. Research has shown that once inside the cell, carbon60 works as a major antioxidant, decreasing toxins, scar tissue, and inflammation. The net effect is a boost in energy, reduced joint pain, greater mobility, improved immunity and digestion, and overall better health.

About four years ago I began researching products containing carbon60 bound to oils such as extra virgin olive oil, coconut oil, and avocado oil. I discovered the healing properties to be so powerful that I started taking them myself and provided them to a select group of customers.

Recently I came across the carbon60 products developed by a company called C360 Health. Their research and patents set them apart, so I chose C360 Health as our provider of carbon60 products such as Thrive Whole Body Health and Thrive Whole Pet Health. Both products combine carbon60 with pure organic extra virgin olive oil and include natural anti-inflammatory ingredients. Thrive Whole Body Health is an especially strong antioxidant supplement that is also highly effective at helping to reduce inflammation and toxicity throughout the body.

Carbon60 demonstrates the strongest antioxidant currently known (270 times stronger than vitamin C) and enhances cell function by negating oxidative stressors (free radicals). Potent, natural, anti-inflammatory ingredients such as L-carmosine, Serratiopeptidase, and CoQ10 have been added in Thrive Whole Body Health to dramatically reduce inflammation throughout the body. This reduction in inflammation improves cognitive focus, gut health, joint flexibility, mobility and reduces pain. It also detoxifies the body and supports the immune system, bringing the body back to balance. Most people and animals (dogs, cats, & horses) exhibit marked improvement within 2-4 weeks, however many customers have reported more immediate results.

Thrive Carbon60 (c60)

Benefits include: 1) Increases vitality, energy, and stamina, 2) Provides powerful antioxidant, anti-inflammatory and detoxification properties, 3) Balances and supports a healthy immune system, 4) Helps address symptoms of both acute and chronic inflammation, and 5) Helps oxygenate the tissues for faster muscle recovery and 6) Helps rebuild soft tissue and reduces scar tissue.

Over the next few months I’ll be sharing more about the science behind carbon60 and the potential for these products to  pave the way to a healthier society. For now, you can find Thrive Whole Body Health and Thrive Whole Pet Health on our website. If you want to try an antioxidant / anti-inflammatory product that sits at the very edge of emerging science, carbon60 is for you, and Thrive Whole Body Health and Thrive Whole Pet Health are the very best on the market.

Yours in Health,
Hank Liers, PhD

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IMMUNE CHARGE+ SHOT SUPER IMMUNITY FORMULA

Dr. Hank Liers, PhD immune charge+ liposomal shot formula

Recently our friends at Quicksilver Scientific introduced a therapeutic “shot” formula called IMMUNE CHARGE+™. This unique product takes immune support to the next level. It is a potent, high-dose liposomal blend of foundational vitamins C, A, D, E, K1, K2, and Haschberg European black elderberry — all delivered in a single 12 ml (0.4 ounce) shot that supports your body’s first-line defenses against unexpected health challenges.

I am highly impressed with IMMUNE CHARGE+ shot formula. Most people, including myself, feel its effects almost instantly after taking a shot and holding it for 30 seconds in the mouth before swallowing it. This is due to the 1) amazing properties of liposomal delivery and 2) therapeutic levels of key ingredients.

If you’re looking for an immune boost that will take you through your day, I can’t think of a better product. Even if you’re already supporting yourself with supplements, I recommend IMMUNE CHARGE+ for those times when you need an extra boost to your immune system.

IMMUNE CHARGE+ supports respiratory health and function, powers healthy inflammatory response to unwanted invaders, and has unsurpassed bioavailability of both premium elderberry (without the sugar load in typical extract) and known immune-support vitamins.

immune charge+ shot liposomal formula

BENEFITS & APPLICATIONS OF IMMUNE CHARGE+ SHOT

IMMUNE CHARGE+ is an intentional mix of six bioavailable vitamins that work synergistically to promote respiratory strength, cellular integrity, and year-round resiliency. Combined with Haschberg European elderberry, known for its immune system benefits — finally in a form your body can use — the result is a powerful liposomal “shot” for immune defenses.

• Activates a robust immune response
• Boosts white blood cell production
• Protects against respiratory pathogens
• Enhances barrier integrity of lung, gut and skin epithelial cells
• Supports cellular integrity
• Quenches excessive pathogen induced inflammation
• Optimizes cellular redox state to enhance defense against pathogens
• Reduces cold duration and symptoms

One shot of IMMUNE CHARGE+ contains: Liposomal Vitamins C (2,000 mg), Vitamin D3 (10,000 IU), Vitamin A (7,500 mcg; 25,000 IU as palmitate), Vitamin E (40 mg Delta Gold Tocotrienols), Vitamins K1 & K2 (1,050 mcg), and Haschberg Elderberry Extract (200 mg) (ElderCraft®)†. Other ingredients include: water, glycerin, ethanol, phospholipids (from sunflower lecithin), Vitamin E (as tocofersolan), citric acid, and natural citrus oils).

IMMUNE CHARGE+ SHOT SUPERCHARGES IMMUNITY

IMMUNE CHARGE+ supercharges the immune system.  It is in a class by itself when compared with other immune support formulas—offering rapid liposomal delivery—and thereby unparalleled bioavailability of its immune-bolstering ingredients. In addition to kicking off a robust immune response and up-regulating white blood cell production, Immune Charge+ formula protects cells from pathogen-induced harm and attenuates excessive inflammation.

Health Products Distributors, Inc. normally sells IMMUNE CHARGE+ in cases of 12 shots, but for a limited time we are selling it in smaller amounts (as little as one bottle) so customers like you can experience these powerful effects! Order a bottle or two (or more), and see how effectively it works for you.

immune charge plus shot formula liposomal delivery system

IMMUNE CHARGE+ SHOT INGREDIENTS

VITAMIN C

Vitamin C (ascorbic acid) offers multifaceted support to the immune system, supporting cellular integrity, antioxidant status, and respiratory function during viral infection.

SUPPORT BARRIER INTEGRITY
The epithelial cells of the skin, lungs, and gastrointestinal tract serve as a first-line of defense against microbial invaders, including viruses responsible for respiratory infections such as colds and the flu. Vitamin C supports epithelial barrier integrity, enhancing the function of these fundamental defense systems.

ANTIOXIDANT PROPERTIES
Vitamin C is a potent reducing agent, meaning it readily donates electrons to electron-deficient recipient molecules (also referred to as free radicals), stabilizing their biochemical structure and inhibiting a chain reaction of oxidative stress. Vitamin C’s ability to terminate these harmful chain reactions makes it one of the body’s most crucial antioxidants. In fact, vitamin C is the body’s primary non-enzymatic, water- soluble antioxidant in blood plasma and tissues. The potent antioxidant properties of vitamin C make it a valuable ally for optimal immune function.

Bacterial and viral infections trigger the production of free radicals by immune cells. While these free radicals have an essential purpose — to activate the innate immune response and directly destroy invading pathogens such as RNA viruses — they also have the unintended consequence of damaging our own cells and organs, such as the lungs.Vitamin C attenuates pathogen-induced free radical damage, protecting cells from harm while the immune system is hard at work eradicating infection.

Vitamin C also boosts the activity of other antioxidants vital to the immune system. It recycles the fat-soluble antioxidant Vitamin E and increases endogenous levels of glutathione, the body’s premier antioxidant that also fine-tunes the innate immune response to viral infections.

Respiratory Health
Vitamin C also protects the lungs during severe respiratory infections. Vitamin C increases the resistance of chicken tracheal cells to infection with the avian coronavirus. It also shortens the duration of convalescence from bacterial pneumonia, a common consequence of severe viral respiratory infections.

Inhibits Virus-Induced Inflammation
Viruses activate the NLRP3 inflammasome, a multiprotein complex that plays a crucial role in innate immunity and the production of pro-inflammatory cytokines. Excessive NLRP3 activation contributes to a phenomenon called a “cytokine storm,” an overproduction of immune cells and their activating products, cytokines. Cytokine storms occur in the end stages of severe infections, causing symptoms such as acute lung inflammation and fluid buildup in the lungs. The cytokine storm can thus severely sicken, and sometimes kill, patients. Attenuation of NLRP3 inflammasome activity may inhibit excessive inflammation in viral infections. Vitamin C inhibits the NLRP3 inflammasome and may thus help inhibit virus-induced inflammation.

Emerging research suggests that intravenous Vitamin C is useful for the treatment of severe viral infections. Unfortunately, vitamin C IVs may not be accessible to many infected patients. Liposomal vitamin C has been found to offer a greater degree of bioavailability as intravenous (IV) vitamin C in a more convenient and less invasive delivery system.

Antiviral Immune Response
Finally, vitamin C is an essential factor in the antiviral immune response to viral respiratory infections, such as influenza H3N1, through increased production of interferon-α/β. It also stimulates phagocytosis, neutrophil chemotaxis, and T-cell development and maturation, crucial processes for fighting pathogenic bacteria and viruses.

VITAMIN A

Vitamin A maintains epithelial barriers in the human body, including the epithelial lining of the lungs and the gut mucosa, where a significant portion of the immune system resides. Vitamin A deficiency compromises immunity in the lungs, rendering them more susceptible to respiratory infections. Vitamin A deficiency also impairs the immune response to intranasal vaccination for respiratory syncytial virus (RSV), a human virus that causes respiratory infections, thus suggesting that this nutrient is crucial for the development of the host immune response to envelope viruses. Altered Vitamin A metabolism is also suspected to play a role in the pathogenesis of influenza.

Conversely, Vitamin A sufficiency, and supplementation reduce susceptibility and mortality in numerous preclinical and clinical models of viral infection. In preclinical research, animals fed Vitamin A-deficient diets suffer from more severe coronavirus infections than those fed vitamin A-sufficient diets. High-dose supplemental vitamin A also enhances the immunoglobulin response to influenza A virus.

Finally, Vitamin A supports immune homeostasis by activating immune cells when they are needed to combat infectious threats while attenuating excessive inflammation.

VITAMIN D

Vitamin D has pleiotropic benefits for immunity. Vitamin D receptors (VDR) are present on most immune cells, indicating their indispensability as components of the immune system.24 Vitamin D deficiency has repeatedly been independently associated with an increased risk of viral infections.

Vitamin D modulates both the innate and adaptive immune responses to respiratory viruses. In the presence of viral infection, lung epithelial cells convert inactive vitamin D into the active form, increasing the expression of a peptide called cathelicidin, which has antiviral effects. Vitamin D also modulates the immune response to respiratory viruses and protects the lungs from damage caused by pro-inflammatory LPS.

VITAMIN E

Vitamin E is a fat-soluble antioxidant that protects the polyunsaturated fatty acids in cell membranes from oxidative damage, which can be triggered by microbial infections. It increases white blood cell proliferation, immunoglobulin levels, natural killer cell activity, and antibody activity, thus supporting broad-spectrum immune function. In our formula, we use a special form of Vtamin E called DeltaGOLD® tocotrienols, which offer fifty times the antioxidant activity of tocopherols, the form of Vitamin E used in most competitors supplements.

VITAMINS K1 AND K2

Vitamins K1 and K1 are fat-soluble vitamins that work in synergy with Vitamins A, D, and E to support healthy immune function. Vitamin K1 (phylloquinone) has anti-inflammatory properties through inhibition of the NF-κB pathway. Vitamin K2 modulates the immune system, decreasing immune reactivity and helping to manage the inflammatory response.

ELDERBERRY

Elderberry is a small dark purple berry that has been used for centuries in traditional herbalism as an aid to the immune system. In this formula, we use Haschberg variety European black elderberry, known for its high potency in anthocyanin flavonoids.

Modern herbalists know that elderberry’s high-concentration anthocyanin flavonoids have vast potential to kickstart immunity, especially upper respiratory function. In this one-of-a-kind, highly bioavailable formulation, we’ve combined it with proven immunity supporting Vitamins A and C — without the added sugar normally found in elderberry products.

When unwanted invaders irritate the immune system and turn up inflammation, other star performers Vitamins A and D work with elderberry to strengthen and fortify your body by helping to balance inflammatory and immune responses. Highly bioavailable Vitamin E kicks in with 50 times the antioxidant activity of typical tocopherols, alongside Vitamins K1 and K2, which help manage the body’s positive inflammatory response.

ANTIVIRAL AND ANTIBACTERIAL ACTIVITY

Elderberry has direct antiviral activities, demonstrating mild inhibitory effect at the early stage of viral infection and a considerably stronger response in the later stages of infection.Elderberry exerts antiviral effects by blocking the function of hemagglutinin (HA) glycoproteins present on the surface of viruses, such as the influenza virus and coronaviruses. When the binding of these spikes to host cells is inhibited, viruses cannot enter the host cell to replicate and cause infection. Elderberry also binds to neuraminidase (NA), an enzyme necessary for viral replication, as indicated by mass spectrometry and molecular docking studies.

The ability of Elderberry to target viruses through multiple pathways may make it unlikely to trigger antiviral resistance, a common problem with antiviral pharmaceutical drugs. Given these findings, it is no surprise that a meta-analysis of RCTs found elderberry supplementation effective for the treatment of upper respiratory symptoms, which are frequently caused by viruses. In fact, one study found that overseas travelers using elderberry for 10 days before traveling and up to five days after arriving experienced a two-day shorter duration of the cold (on average), along with noticing a reduction in symptom severity.

Elderberry’s antimicrobial activity is not limited to its effects on viruses. It also inhibits the growth of clinically relevant bacteria that can cause infections, such as pneumonia that are secondary to infection with a respiratory virus.

IMMUNOMODULATORY PROPERTIES

Elderberry is an immune modulator, enabling a robust immune response while inhibiting excessive inflammation. Elderberry also coordinates a more efficient immune response by mobilizing antiviral innate immune defenses, including the release of the cytokines IL-6 and IL-8. The antioxidant anthocyanins found in elderberry may quench excessive inflammation triggered by a viral infection and promote the growth of beneficial gut bacteria, many of which have immune-enhancing properties.

BENEFICIALLY ALTERS CELLULAR REDOX STATE

Finally, Elderberry also fine-tunes the cellular redox state, or the balance between reactive oxygen species (ROS), reactive nitrogen species (RNS), and their scavenging by antioxidant compounds. The cellular redox state plays a critical role in the immune defense against viral invaders. When ROS and RNS accumulate in viral infections and antioxidant systems are depleted, a severe inflammatory response called a “cytokine storm” can occur. The cytokine storm incites a massive release of inflammatory mediators called cytokines that damage vital tissues such as the heart and lungs. Elderberry phytochemicals called anthocyanins boost the cellular redox potential, enhancing cellular resilience against pathogens.

IMMUNE CHARGE+ SUPPLEMENT FACTS TABLE

Other Ingredients: water, glycerin, ethanol, phospholipids (from purified sunflower lecithin), Vitamin E (as tocofersolan), citric acid, and natural citrus oils.

SUGGESTED USE FOR IMMUNE CHARGE+ SHOT FORMULA

Occasional Use: If you normally take our foundational supplements consisting of a therapeutic multivitamin, essentials fats with vitamin E, a powerful Vitamin C /Antioxidant formula, Vitamin D, and Rejuvenate! PLUS or Rejuvenate! Berries & Herbs, then take one (1) shot of IMMUNE CHARGE+ whenever you expect to be in a situation where you may be exposed to microbial attack.

Regular Use: Take one (1) shot of IMMUNE CHARGE+ daily for up to ten days. Thereafter, take up to four (4) shots per week, or as directed by your healthcare professional.

Intensive Use: Take two (2) shots of IMMUNE CHARGE+ daily for up to five days. Thereafter, take up to four (4) shots per week, or as directed by your healthcare professional.

Directions: Hold IMMUNE CHARGE+ shot in mouth 30 seconds or more before swallowing. Take on an empty stomach at least 10 minutes before meals. Use within 60 days of opening. If pregnant consult a physician. Store at room temperature. Refrigerate after opening.

Quicksilver Delivery Systems® utilizes modern science to unleash the curative power of nature. With the world’s most advanced phospholipid delivery systems, Quicksilver Scientific supplements can help to nourish your cells and fortify your body as they deliver their core effective ingredients faster and more efficiently.

The Phospholipid Encapsulation System brings the power of intravenous therapy into a convenient oral delivery. The Quicksilver delivery system improves upon liposomal technology providing smaller, more stable, single-layer spheres made from the highest-grade ingredients available.

In addition to exceptional absorption rates, Quicksilver’s nanospheres have the demonstrated ability to cross the blood-brain barrier, deposit their cargo intracellularly, and enter lymphatic circulation. Additionally, the phospholipids that compose the liposome shell (primarily phosphytidtylcholine) feed the cell membranes. This ensures proper function for absorption of nutrients, and excretion of cellular waste products and toxins.

† ElderCraft® is a registered trademark, exclusively licensed to Ipona AG/SPA

Learn more about IMMUNE CHARGE+ shot, liposomally delivered immune-boosting formula: https://www.integratedhealth.com/immune-support/immune-charge/

Visit our website: www.IntegratedHealth.com

immune charge plus liposomal shot bottle

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IMMUNE ASSIST 24/7 ORGANIC MEDICINAL MUSHROOM EXTRACT TABLETS – NEW PRODUCT!

Dr. Hank Liers, PhD immune assist 24/7 medicinal mushroom extracts

These days there’s a lot of attention being focused on natural ways to boost immunity. Today I want to introduce you to a new immune system support supplement called Immune Assist 24/7™.

You may already be familiar with Immune-Assist Daily Formula, a product providing significant amounts of organic polysaccharide mushroom extracts I designed a few years ago. The mushrooms included in my original Immune-Assist Daily Formula are Agaricus blazei, Cordyceps sinensis and Cordyceps miltitaris, Lentinula edodes (shiitake), Grifola frondosa (maitake), Ganoderma lucidum (Reishi), and Coriolus versicolor.

INTRODUCING IMMUNE ASSIST™ 24/7

Immune Assist 24/7™ contains the same ingredients as Immune-Assist Daily Formula, but with a few significant additions. The formula includes more than 200 polysaccharides including beta-glucans and hetero-polysaccharides which combine both alpha- and beta-bound monosaccharides into the same molecule. This is a major reason that it shows a massive range of immuno-modulation bioactivity. Included among the important substances are Arabinoxylane, Lentinan, Grifolan (Dr. Nanba’s original Maitake D-Fraction), PSK and PSP, and Active Hemicellulose Correlated Compound (AHCC).

immune assist 24/7 organic medicinal mushroom extract tablets

Medicinal mushroom research has focused on discovering compounds that modulate, positively or negatively, the biological response of immune cells. Many mushroom-derived polysaccharides appear to fit the criteria for biological response modifier (BRM) compounds. They cause no harm and place no additional stress on the body, they assist the body in adapting to various environmental and psychological stresses, and they support the major systems, including nervous, hormonal, and immune systems, as well as regulatory functions.

In addition to the ingredients found in Immune-Assist Daily Formula, Immune Assist 24/7 contains the whole powder from organic Cordyceps sinensis and Cordyceps militaris that includes the mycelium, primordia, fruiting bodies, spores, and extracellular compounds. And here’s the bonus: each tablet contains 80 mg of the powerful antioxidant and Nrf2 activator epigallocatechin gallate (EGCG) extracted from organic green tea leaf. This is a really smart upgrade!

BENEFITS OF ORGANIC MEDICINAL MUSHROOMS IN IMMUNE ASSIST 24/7

The benefits of Immune Assist 24/7 include powerful support for enhanced energy production, anti-aging, improved athletic performance, heart function, lung function, and blood formation. Human, animal, and in vitro studies confirm that the ingredients in this formula consistently and effectively boost immune system function in the following ways:

• Stimulates cytokine (IL-2, IL-12, TNF, and Interferon) production, which stimulates immune function
• Increases Natural Killer (NK) cell activity
• Increases the formation of explosive granules within NK cells
• Increases the number and the activity of lymphocytes, specifically increasing T Cells
• Increases Interferon levels and stimulates NK Cell activity
• Increases the formation of TNF, a group of proteins that help destroy out-of-balance cells
• It is rich in adenosine and amino acids necessary for the production of ATP.
• Cordyceps has been shown to maintain healthy inflammation levelsimmune assist 24/7 organic medicinal mushroom extract tablets

IMMUNE ASSIST 24/7 INGREDIENTS

One tablet of Immune Assist 24/7 contains 960 mg of a proprietary organic blend of mushrooms, described above, and grown on organic white milo (growing substrate); organic green tea leaf extract; and an organic vegetarian base of FibregumBio™ (organic gum acacia) and organic carnauba wax. There are 45 servings per container of 90 tablets.

If you’d like to learn more about the amazing health benefits of medicinal mushrooms, I highly recommend Healing Mushrooms by Dr. Georges Halpern, MD, PhD. You can read the entire book for free (https://www.academia.edu/20332538/Healing_Mushrooms_by_Georges_Halpern).

Health Products Distributors has been selling Immune-Assist Daily Formula for more than 10 years, and it remains one of our top-selling supplements. During this health crisis we have totally sold out of this product and are waiting for new inventory. Because regular Immune-Assist Daily Formula is out of stock, I recommend Immune Assist 24/7 in order to support our customers.

I am pleased to acknowledge Immune Assist 24/7 is a very powerful immune-boosting and health enhancing supplement. If there is an immune system support supplement as potent as Immune-Assist Daily Formula, it might just be this one!

– Hank Liers, PhD

MEDICINAL MUSHROOM RESOURCES

Immune Assist 24/7 (tablets)

Immune-Assist Daily Formula (capsules)

Immune Strengthening Using Medicinal Mushrooms by Hank Liers, PhD

Immune-Assist Research Summary

Healing Mushrooms by Georges Halpern, MD, PhD

immune assist 24/7 organic medicinal mushroom extract tablets

 

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ULTIMATE PROTECTOR+ BRUNSWICK LABS ORAC6.0 TEST REPORT

Dr. Hank Liers, PhDHPDI’s new product ULTIMATE PROTECTOR+ is a next generation cell protection formula that simultaneously meets the needs for high levels of Vitamin C, full spectrum antioxidants* (high ORAC values), and protective enzyme activators (Nrf2 activators from plant-based polyphenols) in a single product. This potent combination of characteristics distinguishes the formula because no other single product available today offers such complete protection.

All three of ULTIMATE PROTECTOR+‘s components provide significant protection against the various types of free radicals that cause cellular damage in the body. In particular, the full spectrum of antioxidants derived from high ORAC fruits, vegetables, and herbs (as well as Vitamin C) provide extremely powerful exogenous sources of protection against oxidative stress. To obtain a quantitative measure of just how powerful these external sources are we have elected to conduct ORAC testing.

ORAC TESTS

ORAC (standing for “Oxygen Radical Absorption Capacity”) was developed by Brunswick Labs as an analytical tool for estimating the antioxidant capacity of substances. It is an in vitro test that was an important advancement in commercially available analysis of the peroxyl free-radical’s trapping ability of foods and ingredients. It has become a de facto standard in the natural products industry. However, the original ORAC method was considered to be just a starting point for comprehensive antioxidant analysis.

The fact is that there are a variety of “free radicals” that operate in humans — the most important of which are the primary radicals hydroxyl, peroxyl, peroxynitrite, singlet oxygen, and superoxide anion. Brunswick Labs has reported that even though the peroxyl is the major free radical in the body, it represents no more than 27% of the total antioxidant potential of selected fruits and vegetables. In addition, the original ORAC method favors certain antioxidant substances over others (e.g., anthocyanins over carotenoids) due to the use of a single free radical source (peroxyl radical).

These radicals are formed, behave, and are defended against differently. They all contribute to: 1) a general condition called “oxidative stress,” or cellular damage, and 2) broad human health concerns caused, for example, by inflammation, and DNA and protein damage. They are each implicated in different health problems – from cardiovascular disease to macular degeneration and Alzheimer’s disease and to skin damage and aging. Below we provide a brief summary of these free radicals.

The Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification. Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes (such as SOD and glutathione). It can damage virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure. Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.

Singlet Oxygen is generated in the skin by by UV. In vivo, it is linked to the oxidation of LDL cholesterol and cardiovascular disease. Singlet oxygen is highly unstable and durable. Carotenoids are very effective at scavenging singlet oxygen. Superoxide Anion is a precursor of all other reactive oxygen species and sometimes is referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage. Antioxidants that scavenge superoxide anion also help prevent the formation of radicals such as hydrogen peroxide and hydroxyl. Superoxide anion has been linked to hypertension and cardiovascular damage.

Recently, Brunswick Labs has introduced a new test called ORAC6.0. This test expands the ORAC platform to measure the antioxidant capacity against each of the five primary reactive oxygen species mentioned above as well as Hypochlorite (HOCl) which is another important free radical that is commonly found in the body as a by-product of the metabolism of other free radicals. Direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions. ORAC6.0 substantially improves broad-spectrum antioxidant analysis and gives evidence of the diverse antioxidant potential of natural products against radicals other than just peroxyl.  Brunswick Labs’ research shows that the antioxidants found in a wide range of natural products are effective against these primary radicals, and that in many cases a preponderance of a product’s antioxidant capacity is described by performance against the six free radicals included to the ORAC6.0 panel.

RESULTS OF ULTIMATE PROTECTOR+ ORAC6.0 TEST

Recently [August/2019] Brunswick Labs has tested ULTIMATE PROTECTOR+™ using the new ORAC6.0 tests. The results reveal an incredible overall ORAC6.0 value of 272,743 µmole TE/gram (i.e., 272,743 per gram!). In addition, the results show that the formula offers excellent protection against all of the six types of free radicals. Specifically, the results show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of ULTIMATE PROTECTOR+™ containing 3.55 grams of the formula.

The overall daily ORAC6.0™ value for six capsules  obtained by adding the values for each free radical type is 968,237 units (272,743 units x 3.55 g)! To the best of our knowledge there is no other product that even comes close to providing such complete protection both in terms of breadth of coverage and overall strength. The Brunswick Labs ORAC6.0™ test results for ULTIMATE PROTECTOR+™ are posted on our blog.


Ultimate Protector+ nrf2 activator formula

 

The bottom line is that you (or anyone) can stand to benefit dramatically from an advanced antioxidant formula that provides exceedingly high ORAC6.0 values and hence amazingly high cell protection…with just a modest daily dose of six small capsules. If you are at all interested to see how well this formula can protect your heath, then we suggest you try a bottle. See for yourself how ULTIMATE PROTECTOR+™ acts to provide you with the ultimate level of protection against free radicals. It’s 100% guaranteed.

ULTIMATE PROTECTOR+™ ORAC6.0 Units Per Serving (six capsules)

ORAC6.0 Units
Per Serving*

Free Radical Type
11,985 Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification.
19,770 Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes. It damages virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure.
9,791 Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.
121,300 Singlet Oxygen is generated in the skin by UV exposure. It is linked to the oxidation of LDL cholesterol and cardiovascular disease.
787,624 Superoxide Anion is a precursor of all other reactive oxygen species – sometimes referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage.

17,768

Hypochlorite HOCl – direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions.

968,237

Total ORAC6.0 Per Daily Serving of Six Capsules (3.55 g)

View the Brunswick Labs Ultimate Protector™ ORAC6.0 Test Report Here

 

ULTIMATE PROTECTOR+™ contains USP-grade non-GMO Vitamin C, SFB® standardized fruit blend (~50% polyphenols, high-ORAC powder: 9,000 µmole TE/g) from Grape, Cranberry, Pomegranate, Blueberry, Apple, Mangosteen, Bilberry, Chokeberry, and Goji Berry), Curcumin (standardized extract with 95% curcuminoids), Trans-Resveratrol (98% from Giant Knotweed), Green Tea Extract (93% polyphenols, 50% EGCG), VinCare® Whole Grape Extract (>80% polyphenols, ORAC>19,000 µmole TE/g), Calcium Malate, Magnesium Malate, and Bioperine® (a patented black pepper extract that enhances absorption of all ingredients and is a known Nrf2 activator).

* Full-spectrum antioxidants in Ultimate Protector+ include polyphenols, flavonoids, anthocyanidins, oligomeric proanthocyanidins, catechins, curcuminoids, ellagic acid, pterostilbene, resveratrol, chlorogenic acid, xanthines, punicalagins, quercetin, zeaxanthin, carotenoids, polysaccharides, quinic acid, and others.

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ULTIMATE PROTECTOR+ NRF2 ACTIVATOR FORMULA – NEW DESIGN!

Dr. Hank Liers, PhD ultimate protector+ antioxidant Nrf2 activator formulaToday I discuss HPDI’s newly updated ULTIMATE PROTECTOR+ antioxidant, cell protection, and Nrf2 activator formula. I first formulated Ultimate Protector in 2012 after I learning about plant-based Nrf2 activators.

My original idea behind developing Ultimate Protector was to unite three design elements in a single formula preventing and ameliorating free-radical damage in the body. I recently updated Ultimate Protector (now Ultimate Protector+) based on availability of improved ingredients and additional research studies on Nrf2 activators.

ULTIMATE PROTECTOR+ ADVANCED CELL PROTECTION & NRF2 ACTIVATOR FORMULA

The three design elements include: 1) non-GMO Vitamin C, 2) high ORAC5.0 antioxidants, and 3) multiple plant-based Nrf2 activators. Nrf2 activators cause release of Nrf2 proteins that are bound in every call of the body. Once released they migrate to the cell nucleus where they cause genetic transcription of antioxidant enzymes that can neutralize excess free-radicals in the body.

THREE ELEMENTS OF ULTIMATE PROTECTOR+ FORMULA

1 – NON-GMO VITAMIN C

The new Ultimate Protector+ includes the same amount of Vitamin C as before—owing to its ability to rapidly reduce superoxide and nitroxide radicals, and scavenge hydroxyl, alkoxyl, and peroxyl radicals. Vitamin C also reacts with non-radical species like singlet oxygen and hypochlorous acid. Vitamin C ‘recycles’ other antioxidants (in its role as electron donor) and allows them to quench more free radicals. Vitamin C itself was recently shown to be a Nrf2 activator.

ultimate protector+ nrf2 activator formula uses three modes of action

Ultimate Protector+ uses three modes of action

2 – HIGH-ORAC6.0 VALUE INGREDIENTS

By means of carefully choosing plant ingredients with the highest ORAC 6.0 values, the product can neutralize all five major types of free radicals commonly found in the body, including: 1) peroxyl, 2) hydroxyl, 3) peroxynitrite, 4) singlet oxygen, and 5) superoxide anion. Ultimate Protector+ includes many plant-based ingredients with high ORAC6.0 values. These include green tea extract, whole grape extract, curcumin, resveratrol, bilberry, and mangosteen.

Brunswick Labs tested Ultimate Protector+™using the ORAC6.0™ test. The results reveal an extremely high overall ORAC6.0 value of 272,743 µmole TE/gram (i.e., 272,743 per gram!). In addition, the results show that the formula offers excellent protection against all six types of free radicals measured. Specifically, the results show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of Ultimate Protector+™ containing 3.55 grams of the formula.ORAC6.0 test results

The overall daily ORAC6.0™ value for six capsules obtained by adding the values for each free radical type is 968,237 units (272,743 units multiplied by 3.55 gram (serving size)! To my knowledge, no other product comes close to providing such complete protection both in terms of breadth of coverage and overall strength. For a fuller explanation of Brunswick Labs ORAC6.0™ test results for Ultimate Protector+™ please read my article “Ultimate Protector+ Brunswick Labs ORAC6.0 Test Report.”

3 – POTENT NRF2 ACTIVATORS

The science on Nrf2 activators clearly shows a wide variety of plant polyphenols act endogenously to cause genetic transcription of many protective enzymes, like superoxide dismutase, glutathione transferase, and heme oxygenase. Many well-known, well-researched Nrf2 activators are high ORAC5.0 antioxidants. These first act as antioxidants giving up an electron, and then act as weak pro-oxidants needed to stimulate Nrf2 activity. In Ultimate Protector+ these ingredients include green tea extract, whole grape extract, curcumin, resveratrol, bilberry, and mangosteen. In addition, ingredients such as extracts of apple, blueberry, cranberry, pomegranate, blueberry, apple, chokeberry, and goji berry are shown in studies to be important Nrf2 activators.

ULTIMATE PROTECTOR+ SUMMARY

Ultimate Protector+ is a powerful antioxidant and Nrf2 activator formula. Both ORAC6.0™ test results and user experience confirm its effectiveness for quenching free radicals and preventing or reducing oxidative damage from all major types of free radicals. There is currently no other antioxidant and/or Nrf2 activator formula available that provides the level of cell protection afforded by Ultimate Protector+.

Ultimate Protector+ is available from HPDI: ULTIMATE PROTECTOR+
(https://www.integratedhealth.com/antioxidants/ultimate-protector/)

12 plant-based Nrf2 activators

ULTIMATE PROTECTOR+ RESOURCES

ULTIMATE PROTECTOR+: https://www.integratedhealth.com/antioxidants/ultimate-protector/

ULTIMATE PROTECTOR ORAC6.0™ TEST RESULTS
(https://integratedhealthblog.com/wp-content/uploads/2019/08/up-orac6.pdf)

BLOG ARTICLES

Ultimate Protector+ Brunswick Labs ORAC6.0™ Test Report
https://integratedhealthblog.com/ultimate-protector-brunswick-labs-orac6-0-test-report/

Amazing Healing Potential of Natural Nrf2 Activators:
https://integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/

Preventing Free Radical Damage with Ultimate Protector+:
https://integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/

Ultimate Protector+ Design Considerations: https://integratedhealthblog.com/scientific-basis-ultimate-protector/

Natural Phytochemical Nrf2 Activators for Chemoprevention:
https://integratedhealthblog.com/natural-phytochemical-nrf2-activators-for-chemoprevention/

New Directions For Preventing Free Radical Damage:
https://integratedhealthblog.com/new-directions-for-preventing-free-radical-damage/