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IMMUNE CHARGE+ SHOT SUPER IMMUNITY FORMULA

Dr. Hank Liers, PhD immune charge+ liposomal shot formula

Recently our friends at Quicksilver Scientific introduced a therapeutic “shot” formula called IMMUNE CHARGE+™. This unique product takes immune support to the next level. It is a potent, high-dose liposomal blend of foundational vitamins C, A, D, E, K1, K2, and Haschberg European black elderberry — all delivered in a single 12 ml (0.4 ounce) shot that supports your body’s first-line defenses against unexpected health challenges.

I am highly impressed with IMMUNE CHARGE+ shot formula. Most people, including myself, feel its effects almost instantly after taking a shot and holding it for 30 seconds in the mouth before swallowing it. This is due to the 1) amazing properties of liposomal delivery and 2) therapeutic levels of key ingredients.

If you’re looking for an immune boost that will take you through your day, I can’t think of a better product. Even if you’re already supporting yourself with supplements, I recommend IMMUNE CHARGE+ for those times when you need an extra boost to your immune system.

IMMUNE CHARGE+ supports respiratory health and function, powers healthy inflammatory response to unwanted invaders, and has unsurpassed bioavailability of both premium elderberry (without the sugar load in typical extract) and known immune-support vitamins.

immune charge+ shot liposomal formula

BENEFITS & APPLICATIONS OF IMMUNE CHARGE+ SHOT

IMMUNE CHARGE+ is an intentional mix of six bioavailable vitamins that work synergistically to promote respiratory strength, cellular integrity, and year-round resiliency. Combined with Haschberg European elderberry, known for its immune system benefits — finally in a form your body can use — the result is a powerful liposomal “shot” for immune defenses.

• Activates a robust immune response
• Boosts white blood cell production
• Protects against respiratory pathogens
• Enhances barrier integrity of lung, gut and skin epithelial cells
• Supports cellular integrity
• Quenches excessive pathogen induced inflammation
• Optimizes cellular redox state to enhance defense against pathogens
• Reduces cold duration and symptoms

One shot of IMMUNE CHARGE+ contains: Liposomal Vitamins C (2,000 mg), Vitamin D3 (10,000 IU), Vitamin A (7,500 mcg; 25,000 IU as palmitate), Vitamin E (40 mg Delta Gold Tocotrienols), Vitamins K1 & K2 (1,050 mcg), and Haschberg Elderberry Extract (200 mg) (ElderCraft®)†. Other ingredients include: water, glycerin, ethanol, phospholipids (from sunflower lecithin), Vitamin E (as tocofersolan), citric acid, and natural citrus oils).

IMMUNE CHARGE+ SHOT SUPERCHARGES IMMUNITY

IMMUNE CHARGE+ supercharges the immune system.  It is in a class by itself when compared with other immune support formulas—offering rapid liposomal delivery—and thereby unparalleled bioavailability of its immune-bolstering ingredients. In addition to kicking off a robust immune response and up-regulating white blood cell production, Immune Charge+ formula protects cells from pathogen-induced harm and attenuates excessive inflammation.

Health Products Distributors, Inc. normally sells IMMUNE CHARGE+ in cases of 12 shots, but for a limited time we are selling it in smaller amounts (as little as one bottle) so customers like you can experience these powerful effects! Order a bottle or two (or more), and see how effectively it works for you.

immune charge plus shot formula liposomal delivery system

IMMUNE CHARGE+ SHOT INGREDIENTS

VITAMIN C

Vitamin C (ascorbic acid) offers multifaceted support to the immune system, supporting cellular integrity, antioxidant status, and respiratory function during viral infection.

SUPPORT BARRIER INTEGRITY
The epithelial cells of the skin, lungs, and gastrointestinal tract serve as a first-line of defense against microbial invaders, including viruses responsible for respiratory infections such as colds and the flu. Vitamin C supports epithelial barrier integrity, enhancing the function of these fundamental defense systems.

ANTIOXIDANT PROPERTIES
Vitamin C is a potent reducing agent, meaning it readily donates electrons to electron-deficient recipient molecules (also referred to as free radicals), stabilizing their biochemical structure and inhibiting a chain reaction of oxidative stress. Vitamin C’s ability to terminate these harmful chain reactions makes it one of the body’s most crucial antioxidants. In fact, vitamin C is the body’s primary non-enzymatic, water- soluble antioxidant in blood plasma and tissues. The potent antioxidant properties of vitamin C make it a valuable ally for optimal immune function.

Bacterial and viral infections trigger the production of free radicals by immune cells. While these free radicals have an essential purpose — to activate the innate immune response and directly destroy invading pathogens such as RNA viruses — they also have the unintended consequence of damaging our own cells and organs, such as the lungs.Vitamin C attenuates pathogen-induced free radical damage, protecting cells from harm while the immune system is hard at work eradicating infection.

Vitamin C also boosts the activity of other antioxidants vital to the immune system. It recycles the fat-soluble antioxidant Vitamin E and increases endogenous levels of glutathione, the body’s premier antioxidant that also fine-tunes the innate immune response to viral infections.

Respiratory Health
Vitamin C also protects the lungs during severe respiratory infections. Vitamin C increases the resistance of chicken tracheal cells to infection with the avian coronavirus. It also shortens the duration of convalescence from bacterial pneumonia, a common consequence of severe viral respiratory infections.

Inhibits Virus-Induced Inflammation
Viruses activate the NLRP3 inflammasome, a multiprotein complex that plays a crucial role in innate immunity and the production of pro-inflammatory cytokines. Excessive NLRP3 activation contributes to a phenomenon called a “cytokine storm,” an overproduction of immune cells and their activating products, cytokines. Cytokine storms occur in the end stages of severe infections, causing symptoms such as acute lung inflammation and fluid buildup in the lungs. The cytokine storm can thus severely sicken, and sometimes kill, patients. Attenuation of NLRP3 inflammasome activity may inhibit excessive inflammation in viral infections. Vitamin C inhibits the NLRP3 inflammasome and may thus help inhibit virus-induced inflammation.

Emerging research suggests that intravenous Vitamin C is useful for the treatment of severe viral infections. Unfortunately, vitamin C IVs may not be accessible to many infected patients. Liposomal vitamin C has been found to offer a greater degree of bioavailability as intravenous (IV) vitamin C in a more convenient and less invasive delivery system.

Antiviral Immune Response
Finally, vitamin C is an essential factor in the antiviral immune response to viral respiratory infections, such as influenza H3N1, through increased production of interferon-α/β. It also stimulates phagocytosis, neutrophil chemotaxis, and T-cell development and maturation, crucial processes for fighting pathogenic bacteria and viruses.

VITAMIN A

Vitamin A maintains epithelial barriers in the human body, including the epithelial lining of the lungs and the gut mucosa, where a significant portion of the immune system resides. Vitamin A deficiency compromises immunity in the lungs, rendering them more susceptible to respiratory infections. Vitamin A deficiency also impairs the immune response to intranasal vaccination for respiratory syncytial virus (RSV), a human virus that causes respiratory infections, thus suggesting that this nutrient is crucial for the development of the host immune response to envelope viruses. Altered Vitamin A metabolism is also suspected to play a role in the pathogenesis of influenza.

Conversely, Vitamin A sufficiency, and supplementation reduce susceptibility and mortality in numerous preclinical and clinical models of viral infection. In preclinical research, animals fed Vitamin A-deficient diets suffer from more severe coronavirus infections than those fed vitamin A-sufficient diets. High-dose supplemental vitamin A also enhances the immunoglobulin response to influenza A virus.

Finally, Vitamin A supports immune homeostasis by activating immune cells when they are needed to combat infectious threats while attenuating excessive inflammation.

VITAMIN D

Vitamin D has pleiotropic benefits for immunity. Vitamin D receptors (VDR) are present on most immune cells, indicating their indispensability as components of the immune system.24 Vitamin D deficiency has repeatedly been independently associated with an increased risk of viral infections.

Vitamin D modulates both the innate and adaptive immune responses to respiratory viruses. In the presence of viral infection, lung epithelial cells convert inactive vitamin D into the active form, increasing the expression of a peptide called cathelicidin, which has antiviral effects. Vitamin D also modulates the immune response to respiratory viruses and protects the lungs from damage caused by pro-inflammatory LPS.

VITAMIN E

Vitamin E is a fat-soluble antioxidant that protects the polyunsaturated fatty acids in cell membranes from oxidative damage, which can be triggered by microbial infections. It increases white blood cell proliferation, immunoglobulin levels, natural killer cell activity, and antibody activity, thus supporting broad-spectrum immune function. In our formula, we use a special form of Vtamin E called DeltaGOLD® tocotrienols, which offer fifty times the antioxidant activity of tocopherols, the form of Vitamin E used in most competitors supplements.

VITAMINS K1 AND K2

Vitamins K1 and K1 are fat-soluble vitamins that work in synergy with Vitamins A, D, and E to support healthy immune function. Vitamin K1 (phylloquinone) has anti-inflammatory properties through inhibition of the NF-κB pathway. Vitamin K2 modulates the immune system, decreasing immune reactivity and helping to manage the inflammatory response.

ELDERBERRY

Elderberry is a small dark purple berry that has been used for centuries in traditional herbalism as an aid to the immune system. In this formula, we use Haschberg variety European black elderberry, known for its high potency in anthocyanin flavonoids.

Modern herbalists know that elderberry’s high-concentration anthocyanin flavonoids have vast potential to kickstart immunity, especially upper respiratory function. In this one-of-a-kind, highly bioavailable formulation, we’ve combined it with proven immunity supporting Vitamins A and C — without the added sugar normally found in elderberry products.

When unwanted invaders irritate the immune system and turn up inflammation, other star performers Vitamins A and D work with elderberry to strengthen and fortify your body by helping to balance inflammatory and immune responses. Highly bioavailable Vitamin E kicks in with 50 times the antioxidant activity of typical tocopherols, alongside Vitamins K1 and K2, which help manage the body’s positive inflammatory response.

ANTIVIRAL AND ANTIBACTERIAL ACTIVITY

Elderberry has direct antiviral activities, demonstrating mild inhibitory effect at the early stage of viral infection and a considerably stronger response in the later stages of infection.Elderberry exerts antiviral effects by blocking the function of hemagglutinin (HA) glycoproteins present on the surface of viruses, such as the influenza virus and coronaviruses. When the binding of these spikes to host cells is inhibited, viruses cannot enter the host cell to replicate and cause infection. Elderberry also binds to neuraminidase (NA), an enzyme necessary for viral replication, as indicated by mass spectrometry and molecular docking studies.

The ability of Elderberry to target viruses through multiple pathways may make it unlikely to trigger antiviral resistance, a common problem with antiviral pharmaceutical drugs. Given these findings, it is no surprise that a meta-analysis of RCTs found elderberry supplementation effective for the treatment of upper respiratory symptoms, which are frequently caused by viruses. In fact, one study found that overseas travelers using elderberry for 10 days before traveling and up to five days after arriving experienced a two-day shorter duration of the cold (on average), along with noticing a reduction in symptom severity.

Elderberry’s antimicrobial activity is not limited to its effects on viruses. It also inhibits the growth of clinically relevant bacteria that can cause infections, such as pneumonia that are secondary to infection with a respiratory virus.

IMMUNOMODULATORY PROPERTIES

Elderberry is an immune modulator, enabling a robust immune response while inhibiting excessive inflammation. Elderberry also coordinates a more efficient immune response by mobilizing antiviral innate immune defenses, including the release of the cytokines IL-6 and IL-8. The antioxidant anthocyanins found in elderberry may quench excessive inflammation triggered by a viral infection and promote the growth of beneficial gut bacteria, many of which have immune-enhancing properties.

BENEFICIALLY ALTERS CELLULAR REDOX STATE

Finally, Elderberry also fine-tunes the cellular redox state, or the balance between reactive oxygen species (ROS), reactive nitrogen species (RNS), and their scavenging by antioxidant compounds. The cellular redox state plays a critical role in the immune defense against viral invaders. When ROS and RNS accumulate in viral infections and antioxidant systems are depleted, a severe inflammatory response called a “cytokine storm” can occur. The cytokine storm incites a massive release of inflammatory mediators called cytokines that damage vital tissues such as the heart and lungs. Elderberry phytochemicals called anthocyanins boost the cellular redox potential, enhancing cellular resilience against pathogens.

IMMUNE CHARGE+ SUPPLEMENT FACTS TABLE

Other Ingredients: water, glycerin, ethanol, phospholipids (from purified sunflower lecithin), Vitamin E (as tocofersolan), citric acid, and natural citrus oils.

SUGGESTED USE FOR IMMUNE CHARGE+ SHOT FORMULA

Occasional Use: If you normally take our foundational supplements consisting of a therapeutic multivitamin, essentials fats with vitamin E, a powerful Vitamin C /Antioxidant formula, Vitamin D, and Rejuvenate! PLUS or Rejuvenate! Berries & Herbs, then take one (1) shot of IMMUNE CHARGE+ whenever you expect to be in a situation where you may be exposed to microbial attack.

Regular Use: Take one (1) shot of IMMUNE CHARGE+ daily for up to ten days. Thereafter, take up to four (4) shots per week, or as directed by your healthcare professional.

Intensive Use: Take two (2) shots of IMMUNE CHARGE+ daily for up to five days. Thereafter, take up to four (4) shots per week, or as directed by your healthcare professional.

Directions: Hold IMMUNE CHARGE+ shot in mouth 30 seconds or more before swallowing. Take on an empty stomach at least 10 minutes before meals. Use within 60 days of opening. If pregnant consult a physician. Store at room temperature. Refrigerate after opening.

Quicksilver Delivery Systems® utilizes modern science to unleash the curative power of nature. With the world’s most advanced phospholipid delivery systems, Quicksilver Scientific supplements can help to nourish your cells and fortify your body as they deliver their core effective ingredients faster and more efficiently.

The Phospholipid Encapsulation System brings the power of intravenous therapy into a convenient oral delivery. The Quicksilver delivery system improves upon liposomal technology providing smaller, more stable, single-layer spheres made from the highest-grade ingredients available.

In addition to exceptional absorption rates, Quicksilver’s nanospheres have the demonstrated ability to cross the blood-brain barrier, deposit their cargo intracellularly, and enter lymphatic circulation. Additionally, the phospholipids that compose the liposome shell (primarily phosphytidtylcholine) feed the cell membranes. This ensures proper function for absorption of nutrients, and excretion of cellular waste products and toxins.

† ElderCraft® is a registered trademark, exclusively licensed to Ipona AG/SPA

Learn more about IMMUNE CHARGE+ shot, liposomally delivered immune-boosting formula: https://www.integratedhealth.com/immune-support/immune-charge/

Visit our website: www.IntegratedHealth.com

immune charge plus liposomal shot bottle

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ULTIMATE PROTECTOR+ TRIPLE ACTION NRF2 ANTIOXIDANT SUPPLEMENT – UPDATE

Dr. Hank Liers, PhD ultimate protector+ nrf2 antioxidantFred Liers PhD ultimate protector+ Nrf2 antioxidant formula

There’s a new kind of super-antioxidant formula in town. It will quench your free radicals in ways you never conceived. It’s called Ultimate Protector+. Its benefits are many due to a triple-action design that includes instructing cells to make their own antioxidants, a process known as Nrf2 activation. The benefits range from anti-aging and anti-inflammatory effects to support for immunity, brain function, and cardiovascular health. Your body depends on antioxidants to defend it from oxidative stressors. And Ultimate Protector+ defends you like nothing else can.

Ultimate Protector+ is among the world’s premier Nrf2 antioxidant supplements. It started when Dr. Hank realized that a triple-mode formula could best leverage the antioxidant powers available via Nrf2 activators in supplement form. That is, he could develop an ultra-effective Nrf2 activator-antioxidant formula by combining 1) non-GMO vitamin C, 2) potent exogenous (external) antioxidants from plant substances, and 3) plant-based Nrf2 transcription factor activators for endogenous (internal) antioxidant production within cells.

Dr. Hank designed Ultimate Protector+ to provide the most comprehensive antioxidant protection going beyond any supplement. The proof of his design methodology is the fact that one serving (six small capsules) of Ultimate Protector+ provides nearly 1,000,000 ORAC6.0 units. The ORAC6.0 test from Brunswick Labs measures how effectively an antioxidant can perform against six different free radicals: hydroxyl, peroxyl, peroxynitrite, singlet oxygen, superoxide anion, and hypochlorite (hypchlorous acid).

Ultimate Protector+ nrf2 activator formula

Most antioxidant supplements may effectively quench one or two types of free radicals. What makes Ultimate Protector+ different is its unique capacity to quench all six major free radicals. Ultimate Protector+ provides a significant edge in defending your body against the full spectrum of oxidants encountered in daily life.

The distinctive advantage of balanced free radical defense against a broad spectrum of oxidants distinguishes Ultimate Protector+ as a premier antioxidant and anti-aging supplement. This also makes it a “go-to” formula for supporting strong immunity, mitigating the effects of inflammation, enhancing brain function, boosting cardiovascular health, etc., as well as generally maintaining high antioxidant status in cells.

plant-based antioxidants nrf2 activators ultimate protector+

ULTIMATE PROTECTOR+ TEST RESULTS

Looking at the Brunswick Labs’ ORAC6.0 test results (from August 2019) for Ultimate Protector+, you see various oxidants (hydroxyl radical, peroxyl radical, singlet oxygen, etc.) are quenched at somewhat different levels. What is most important is that all six types are quenched, and that the total level of antioxidant protection—968,237 µmole TE/gram—is extremely high. To get an idea of how high that level of protection is, consider that a typical “good” antioxidant supplement might provide about 7,000–10,000 µmole TE/gram.

Specifically, the test results for Ultimate Protector+ show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of Ultimate Protector+ containing 3.55 grams of the formula.

ORAC6.0 test results

The overall daily ORAC6.0 value for six capsules (3.55 g) is obtained by adding the values for each free radical type. The total of 968,237 units is calculated by multiplying 272,743 units x 3.55 gram serving). To our knowledge there is no other Nrf2 or antioxidant formula that comes close to providing the complete protection of Ultimate Protector+ in terms of breadth of coverage and overall strength.

ULTIMATE PROTECTOR+
PRODUCT INFORMATION

Ultimate Protector+ is a next generation cell protection formula that simultaneously meets the body’s needs for 1) high levels of Vitamin C, 2) full spectrum antioxidants (including polyphenols, flavonoids, anthocyanidins, oligomeric proanthocyanidins, catechins, curcuminoids, ellagic acid, pterostilbene, resveratrol, chlorogenic acid, xanthines, punicalagins, quercetin, zeaxanthin, carotenoids, polysaccharides, quinic acid, and more), and 3) many of the most protective enzyme activators (Nrf2 activators) — in a single product! This potent combination of characteristics distinguishes the formula because no other single formula available today offers such complete protection.

Ultimate Protector+ supplies nutrients that provide anti-aging, anti-inflammatory, and pain relieving effects, as well as ultra-high levels of antioxidant protection. Damage to cells caused by free-radicals contributes to many degenerative health conditions and to the aging process. This formula effectively supports the body in combating adverse effects of free-radicals.

ultimate protector+ triple action antioxidant nrf2 supplement

ULTIMATE PROTECTOR+ BENEFITS

• Anti-aging

• Anti-inflammatory

• Pain relief

• Acts to support the body regarding brain function, cardiovascular conditions, hypertension, and supports strong immunity

• Ultra powerful free radical defense. Helps prevent and mitigate free radical damage that contributes to conditions of poor health.

• Facilitates the body’s internal production of antioxidant enzymes within cells by supplying many powerful natural Nrf2 transcription factor activators

• Ultra effective, high potency, best-in-class antioxidant protection

ULTIMATE PROTECTOR+ FEATURES

• Plant Based Nrf2 Activators Potentiate the Body’s Internal Antioxidant Systems

• Ultra-High Antioxidant Potency as measured by ORAC6.0 testing to be over 968,000 micro moles TE per serving!

• Complete Formula Defends Body Against All Six Major Classes of Free Radicals including: 1) peroxyl, 2) hydroxyl, 3) peroxynitrite, 4) singlet oxygen, 5) superoxide anion, and 6) hypochlorite

• Provides 12+ Fruit- and Vegetable-Based Antioxidants and Nrf2 Activators to Offer Full Spectrum Protection

• Synergistic Formula Combines Effects of Endogenous (Internally Produced) Antioxidants, Exogenous (externally supplied) Antioxidants, and Vitamin C

• 100% non-GMO Ingredients (includes non-GMO Vitamin C)

• Contains calcium and magnesium malates supporting ATP & enzyme production

• Includes BioPerine ® a black pepper extract that significantly enhances the absorption of all of the nutrients in the formula

• Veggie Capsules (suitable for vegetarians and vegans)

• Easy to Take. Just six small capsules daily provides optimal antioxidant protection.

• Best in Class Cell Protection

Ultimate Protector+ provides high levels of antioxidants

ULTIMATE PROTECTOR+ INGREDIENTS

Ultimate Protector+ contains USP-grade non-GMO Vitamin C, SFB® standardized fruit blend (~50% polyphenols, high-ORAC powder: 9,000 µmole TE/g) from Grape, Cranberry, Pomegranate, Blueberry, Apple, Mangosteen, Bilberry, Chokeberry, and Goji Berry), Curcumin (standardized extract with 95% curcuminoids), Trans-Resveratrol (98% from Giant Knotweed), Green Tea Extract (93% polyphenols, 50% EGCG), VinCare® Whole Grape Extract (>80% polyphenols, ORAC>19,000 µmole TE/g), Calcium Malate, Magnesium Malate, and Bioperine® (a patented black pepper extract that enhances absorption of all ingredients and is a known Nrf2 activator).

Ultimate Protector+ is contained in a capsule suitable for vegetarians (i.e., a veggie cap) and contains no magnesium stearate.

ULTIMATE PROTECTOR+ RECAP

Ultimate Protector+ satisfies three distinct needs: 1) The need for a non-GMO Vitamin C product. That is, a Vitamin C formula that avoids genetically modified sources, 2) The need for a single powerful antioxidant formula. That is, a single, easy-to-take antioxidant formula offering a broad range of extremely high ORAC6.0 plant source #antioxidants, and 3) The need for a supplement providing a full spectrum of many of the most powerful Nrf2 activators. That is, a supplement providing a wide range of natural #Nrf2 transcription factor activators that allow the body to make its own antioxidant enzymes (e.g., superoxide dismutase (SOD), catalase, heme oxygenase, and glutathione peroxidase).

Ultimate Protector+ is an invaluable supplement for individuals requiring a high-quality, high-potency, and highly effective antioxidant supplement providing exceptionally well-rounded antioxidant protection against a broad range of free radicals. It has a unique triple action capacity to provide the nutrients required by the body for maximum free-radical defense, including plant-based Nrf2 activators that allow cells to produce their own antioxidants.

Providing nearly one million ORAC6.0 units is just one of the ways Ultimate Protector+ supports optimal health. Combining super antioxidant power with non-GMO vitamin C and Nrf2 activators makes Ultimate Protector+ an ideal choice for anyone seeking the highest levels of antioxidant protection.

ULTIMATE PROTECTOR+ RESOURCES

Ultimate Protector+
(detailed product information)

HPDI BLOG ARTICLES

Amazing Healing Potential of Natural Nrf2 Activators
https://integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/

Ultimate Protector+ Design Considerations
https://integratedhealthblog.com/scientific-basis-ultimate-protector/

New Directions For Preventing Free-Radical Damage
https://integratedhealthblog.com/new-directions-for-preventing-free-radical-damage

Natural Phytochemical Nrf2 Activators for Chemoprevention
https://integratedhealthblog.com/natural-phytochemical-nrf2-activators-for-chemoprevention/

Ultimate Protector+ Brunswick Labs ORAC6.0 Test Report
https://integratedhealthblog.com/ultimate-protector-brunswick-labs-orac6-0-test-report/

Rejuvenation Program Part 4: Foundational Elements in the Master Rejuvenation Program
https://integratedhealthblog.com/the-master-rejuvenation-program-part-4/

VIDEOS

Ultimate Protector+ Phenomenal Test Results! 986,000 ORAC6.0 units Versus Six Types of Free Radicals (https://www.youtube.com/watch?v=klx1YSjCStk)

Dr. Hank Liers Deep Dive: Ultimate Protector+ (https://www.youtube.com/watch?v=TVLQlr_0SyU)

 

 

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MEGAVITAMIN MYTH-BUSTING – ORTHOMOLECULAR MEDICINE NEWS ON VITAMINS

Fred Liers PhD megavitamin myth busting orthomolecular vitamins andrew saul omnsAs the year draws to a close, it is a good time to reflect on the past year, as well as to look forward to the New Year with respect to one’s health goals. This includes assessing your nutritional supplement regimen. There is more confusion about nutritional supplements than ever. With this in mind, we present “Megavitamin Myth-Busting” from Andrew W. Saul, PhD and Helen Saul Case from the Orthomolecular Medicine News Service to clear confusion about vitamins and other nutritional supplements, and set the record straight. Enjoy! ~

MEGAVITAMIN MYTH-BUSTING

Commentary by Andrew W. Saul and Helen Saul Case

(Orthomolecular Medicine News Service, Dec 23, 2019)

People are so confused about endless internet vitamin legends. Now it’s time to be blunt and set the record straight.

The media says that taking vitamins will kill me. Is that so? NO.

 

It’s been said that the FDA does not regulate nutritional supplements. Is that true? NO. “FDA regulates both finished dietary supplement products and dietary ingredients.” [U.S. Food and Drug Administration, http://www.fda.gov/Food/DietarySupplements/ ]

 

I have heard that “vitamin supplements are useless” and that “supplements do not prevent or cure disease, and they do not help you live longer.” Is that accurate? NO.
http://orthomolecular.org/resources/omns/index.shtml

 

I get enough vitamins from my diet. NO, you don’t.
http://www.orthomolecular.org/resources/omns/v01n03.shtml

 

Aren’t foods a more economical vitamin source than supplements? NO.
http://orthomolecular.org/resources/omns/v09n32.shtml

 

Should I really stop all vitamin supplements for a week (or more) prior to surgery? NO.
http://orthomolecular.org/resources/omns/v11n07.shtml

 

Do I need special vitamin preparations for my body to absorb them? NO. With vitamins, there is usually no absorption issue. All animals need and absorb nutrients, including vitamins. If they didn’t, they’d be long extinct. The surface area of your small intestine, if all the nooks and crannies were flatted out, would be half the size of a regulation basketball court. There is ample opportunity for nutrient absorption.

 

Doesn’t taking vitamins just make expensive urine? NO.
http://www.orthomolecular.org/resources/omns/v04n21.shtml

 

VITAMIN C

 

Does vitamin C causes kidney stones? NO.
http://orthomolecular.org/resources/omns/v09n05.shtml

 

Does vitamin C interfere with chemotherapy? NO, vitamin C actually enhances chemotherapy.
http://www.doctoryourself.com/Cancer_Why_IV_C.html and
http://www.doctoryourself.com/chemo.html

 

I have heard that ascorbic acid is not really vitamin C. Is that true? NO.
http://orthomolecular.org/resources/omns/v09n27.shtml and
http://orthomolecular.org/resources/omns/v05n10.shtml

 

Will vitamin C from a genetically modified (GMO) source hurt me? NO.
http://www.orthomolecular.org/resources/omns/v09n27.shtml

 

Does the acidity of ascorbic acid vitamin C destroy probiotics? NO.
http://orthomolecular.org/resources/omns/v09n27.shtml

 

If I take too much vitamin C during pregnancy, will it cause a miscarriage? NO, vitamin C is highly protective of your developing baby.
http://www.orthomolecular.org/resources/omns/v10n06.shtml

 

Does taking too much vitamin C during pregnancy causes infantile rebound scurvy? NO.
http://www.orthomolecular.org/resources/omns/v14n12.shtml

 

Is liposomal vitamin C as good as intravenous vitamin C? NO.
https://www.youtube.com/embed/04cOSwZ43II?autoplay=1

 

Will I get to much sodium from taking sodium ascorbate vitamin C? NO, says cardiologist Thomas Levy, MD, JD.
http://www.orthomolecular.org/resources/omns/v14n12.shtml

 

Does G6PD mean no supplemental vitamin C? NO. The Riordan Clinic has administered 15,000 mg vitamin C by IV to G6PD patients without harm.
http://www.doctoryourself.com/RiordanIVC.pdf

 

But since Linus Pauling died from cancer, didn’t he fail to benefit from all the vitamin C he took? NO.
http://orthomolecular.org/resources/omns/v06n24.shtml

 

VITAMIN A

 

Some persons have a genetic trait that makes it more difficult for them to convert dietary carotene into active vitamin A. Does this mean they must take preformed oil retinol A? NO. Even a poor converter can still make sufficient vitamin A from carotene if they eat lots of fruits and vegetables . . . which we should all be doing anyway.

 

Does beta carotene cause cancer? NO. (But cigarettes do.)
http://www.orthomolecular.org/resources/omns/v04n09.shtml and
http://www.orthomolecular.org/resources/omns/v04n23.shtml

 

B VITAMINS

 

Does niacin hurt the liver? NO.
http://www.doctoryourself.com/news/v4n21.html and
http://www.doctoryourself.com/niacin.html

 

Is niacin clinically incompatible for people with methylation issues? NO. Theoretically, perhaps. But Dr. Abram Hoffer, the world’s most experienced niacin physician, has said it is not clinically significant.

 

Aren’t B-vitamins so poorly absorbed that they need to be methylated? NO. Comparing their molecular weights with the simplest of all sugars, we find:

Glucose (C6H12O6) weighs 180 grams/mole
Niacin (C6H5NO2) weighs 123 g/mol
Pyridoxine 169 g/mol
Pantothenic acid 219 g/mol
Biotin 244 g/mol
Thiamin 265 g/mol
Riboflavin 376 g/mol
Folic acid or folate 441 [Methylated may be better. However: 1) See: Bailey LB. Dietary reference intakes for folate: the debut of dietary folate equivalents. Nutr Rev. 1998;56(10):294-299. And 2) The Linus Pauling Institute says: “Unmetabolized folic acid concentrations returned to baseline levels at the end of the study, suggesting that adaptive mechanisms eventually converted folic acid to reduced forms of folate.”
Cobalamin 1,355 g/mol [methylated is probably better in this case]

 

MAGNESIUM

 

I get plenty of magnesium in my diet! NO, you probably don’t.
http://www.orthomolecular.org/resources/omns/v13n22.shtml and
http://www.orthomolecular.org/resources/omns/v12n20.shtml

 

VITAMIN E

 

Is vitamin E dangerous? NO. The safety record of all forms of vitamin E is exceptionally good.
http://www.orthomolecular.org/resources/omns/v07n11.shtml

 

VITAMIN K

 

Do I need to consume vitamin K-2 because K-1 in foods is ineffective? NO. Your body will make the conversion for you. John Cannell, MD, writes that the conversion “occurs through an intermediary molecule, vitamin K3, which is made in the intestine from vitamin K1. [Hirota Y, et al. J Biol Chem. 2013 Sep 30.] “[M]odern humans are deficient in K2 because they do not eat large quantities of vitamin K1 containing foods. If we look at Paleolithic humans, they probably got high amount of vitamin K2 from eating large quantities of kale and spinach-like foods, very high in K1, which then supplied their tissues with all the vitamin K2 they needed. [A]s far as getting enough vitamin K2, the best thing to do is eat your greens.”

VITAMIN D

I drink milk, and I spend time in the sunshine. Don’t I get plenty of vitamin D? NO. If your shadow is longer than you are, you are not making vitamin D from sunlight, says William Grant, PhD. Thus, little vitamin D is made by your body in the six colder months of the year. This is also true in the summer months if only exposed to sun mornings and afternoons.
http://www.orthomolecular.org/resources/omns/v07n07.shtml

 

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(Andrew W. Saul, OMNS founder and Editor-in-Chief, has coauthored four books with Abram Hoffer, MD, and is editor of the textbook The Orthomolecular Treatment of Chronic Disease. OMNS Assistant Editor Helen Saul Case is the author of The Vitamin Cure for Women’s Health Problems, Vitamins & Pregnancy: The Real Story, and Orthomolecular Nutrition for Everyone.)

 

Nutritional Medicine is Orthomolecular Medicine

Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

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ULTIMATE PROTECTOR+ BRUNSWICK LABS ORAC6.0 TEST REPORT

Dr. Hank Liers, PhDHPDI’s new product ULTIMATE PROTECTOR+ is a next generation cell protection formula that simultaneously meets the needs for high levels of Vitamin C, full spectrum antioxidants* (high ORAC values), and protective enzyme activators (Nrf2 activators from plant-based polyphenols) in a single product. This potent combination of characteristics distinguishes the formula because no other single product available today offers such complete protection.

All three of ULTIMATE PROTECTOR+‘s components provide significant protection against the various types of free radicals that cause cellular damage in the body. In particular, the full spectrum of antioxidants derived from high ORAC fruits, vegetables, and herbs (as well as Vitamin C) provide extremely powerful exogenous sources of protection against oxidative stress. To obtain a quantitative measure of just how powerful these external sources are we have elected to conduct ORAC testing.

ORAC TESTS

ORAC (standing for “Oxygen Radical Absorption Capacity”) was developed by Brunswick Labs as an analytical tool for estimating the antioxidant capacity of substances. It is an in vitro test that was an important advancement in commercially available analysis of the peroxyl free-radical’s trapping ability of foods and ingredients. It has become a de facto standard in the natural products industry. However, the original ORAC method was considered to be just a starting point for comprehensive antioxidant analysis.

The fact is that there are a variety of “free radicals” that operate in humans — the most important of which are the primary radicals hydroxyl, peroxyl, peroxynitrite, singlet oxygen, and superoxide anion. Brunswick Labs has reported that even though the peroxyl is the major free radical in the body, it represents no more than 27% of the total antioxidant potential of selected fruits and vegetables. In addition, the original ORAC method favors certain antioxidant substances over others (e.g., anthocyanins over carotenoids) due to the use of a single free radical source (peroxyl radical).

These radicals are formed, behave, and are defended against differently. They all contribute to: 1) a general condition called “oxidative stress,” or cellular damage, and 2) broad human health concerns caused, for example, by inflammation, and DNA and protein damage. They are each implicated in different health problems – from cardiovascular disease to macular degeneration and Alzheimer’s disease and to skin damage and aging. Below we provide a brief summary of these free radicals.

The Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification. Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes (such as SOD and glutathione). It can damage virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure. Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.

Singlet Oxygen is generated in the skin by by UV. In vivo, it is linked to the oxidation of LDL cholesterol and cardiovascular disease. Singlet oxygen is highly unstable and durable. Carotenoids are very effective at scavenging singlet oxygen. Superoxide Anion is a precursor of all other reactive oxygen species and sometimes is referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage. Antioxidants that scavenge superoxide anion also help prevent the formation of radicals such as hydrogen peroxide and hydroxyl. Superoxide anion has been linked to hypertension and cardiovascular damage.

Recently, Brunswick Labs has introduced a new test called ORAC6.0. This test expands the ORAC platform to measure the antioxidant capacity against each of the five primary reactive oxygen species mentioned above as well as Hypochlorite (HOCl) which is another important free radical that is commonly found in the body as a by-product of the metabolism of other free radicals. Direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions. ORAC6.0 substantially improves broad-spectrum antioxidant analysis and gives evidence of the diverse antioxidant potential of natural products against radicals other than just peroxyl.  Brunswick Labs’ research shows that the antioxidants found in a wide range of natural products are effective against these primary radicals, and that in many cases a preponderance of a product’s antioxidant capacity is described by performance against the six free radicals included to the ORAC6.0 panel.

RESULTS OF ULTIMATE PROTECTOR+ ORAC6.0 TEST

Recently [August/2019] Brunswick Labs has tested ULTIMATE PROTECTOR+™ using the new ORAC6.0 tests. The results reveal an incredible overall ORAC6.0 value of 272,743 µmole TE/gram (i.e., 272,743 per gram!). In addition, the results show that the formula offers excellent protection against all of the six types of free radicals. Specifically, the results show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of ULTIMATE PROTECTOR+™ containing 3.55 grams of the formula.

The overall daily ORAC6.0™ value for six capsules  obtained by adding the values for each free radical type is 968,237 units (272,743 units x 3.55 g)! To the best of our knowledge there is no other product that even comes close to providing such complete protection both in terms of breadth of coverage and overall strength. The Brunswick Labs ORAC6.0™ test results for ULTIMATE PROTECTOR+™ are posted on our blog.


Ultimate Protector+ nrf2 activator formula

 

The bottom line is that you (or anyone) can stand to benefit dramatically from an advanced antioxidant formula that provides exceedingly high ORAC6.0 values and hence amazingly high cell protection…with just a modest daily dose of six small capsules. If you are at all interested to see how well this formula can protect your heath, then we suggest you try a bottle. See for yourself how ULTIMATE PROTECTOR+™ acts to provide you with the ultimate level of protection against free radicals. It’s 100% guaranteed.

ULTIMATE PROTECTOR+™ ORAC6.0 Units Per Serving (six capsules)

ORAC6.0 Units
Per Serving*

Free Radical Type
11,985 Peroxyl Radical is very important in many biological systems, including lipid peroxidation, DNA cleavage, and protein backbone modification.
19,770 Hydroxyl is highly reactive and cannot be eliminated by our endogenous enzymes. It damages virtually all types of macromolecules: carbohydrates, nucleic acids, lipids, and amino acids. In the skin, hydroxyl radicals are created by UV exposure.
9,791 Peroxynitrite is a reactive nitrogen species that is particularly harmful to proteins. It has been implicated in the development of certain cancers, hepatitis, and chronic inflammation. In the skin, peroxynitrite contributes to the breakdown of vital proteins, such as collagen.
121,300 Singlet Oxygen is generated in the skin by UV exposure. It is linked to the oxidation of LDL cholesterol and cardiovascular disease.
787,624 Superoxide Anion is a precursor of all other reactive oxygen species – sometimes referred to as “the mother of free radicals.” It is highly toxic and contributes to lipid and DNA damage.

17,768

Hypochlorite HOCl – direct reaction of HOCl with plasmid DNA gives rise to single- and double-strand breaks via chloramine-mediated reactions.

968,237

Total ORAC6.0 Per Daily Serving of Six Capsules (3.55 g)

View the Brunswick Labs Ultimate Protector™ ORAC6.0 Test Report Here

 

ULTIMATE PROTECTOR+™ contains USP-grade non-GMO Vitamin C, SFB® standardized fruit blend (~50% polyphenols, high-ORAC powder: 9,000 µmole TE/g) from Grape, Cranberry, Pomegranate, Blueberry, Apple, Mangosteen, Bilberry, Chokeberry, and Goji Berry), Curcumin (standardized extract with 95% curcuminoids), Trans-Resveratrol (98% from Giant Knotweed), Green Tea Extract (93% polyphenols, 50% EGCG), VinCare® Whole Grape Extract (>80% polyphenols, ORAC>19,000 µmole TE/g), Calcium Malate, Magnesium Malate, and Bioperine® (a patented black pepper extract that enhances absorption of all ingredients and is a known Nrf2 activator).

* Full-spectrum antioxidants in Ultimate Protector+ include polyphenols, flavonoids, anthocyanidins, oligomeric proanthocyanidins, catechins, curcuminoids, ellagic acid, pterostilbene, resveratrol, chlorogenic acid, xanthines, punicalagins, quercetin, zeaxanthin, carotenoids, polysaccharides, quinic acid, and others.

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ULTIMATE PROTECTOR+ NRF2 ACTIVATOR FORMULA – NEW DESIGN!

Dr. Hank Liers, PhD ultimate protector+ antioxidant Nrf2 activator formulaToday I discuss HPDI’s newly updated ULTIMATE PROTECTOR+ antioxidant, cell protection, and Nrf2 activator formula. I first formulated Ultimate Protector in 2012 after I learning about plant-based Nrf2 activators.

My original idea behind developing Ultimate Protector was to unite three design elements in a single formula preventing and ameliorating free-radical damage in the body. I recently updated Ultimate Protector (now Ultimate Protector+) based on availability of improved ingredients and additional research studies on Nrf2 activators.

ULTIMATE PROTECTOR+ ADVANCED CELL PROTECTION & NRF2 ACTIVATOR FORMULA

The three design elements include: 1) non-GMO Vitamin C, 2) high ORAC5.0 antioxidants, and 3) multiple plant-based Nrf2 activators. Nrf2 activators cause release of Nrf2 proteins that are bound in every call of the body. Once released they migrate to the cell nucleus where they cause genetic transcription of antioxidant enzymes that can neutralize excess free-radicals in the body.

THREE ELEMENTS OF ULTIMATE PROTECTOR+ FORMULA

1 – NON-GMO VITAMIN C

The new Ultimate Protector+ includes the same amount of Vitamin C as before—owing to its ability to rapidly reduce superoxide and nitroxide radicals, and scavenge hydroxyl, alkoxyl, and peroxyl radicals. Vitamin C also reacts with non-radical species like singlet oxygen and hypochlorous acid. Vitamin C ‘recycles’ other antioxidants (in its role as electron donor) and allows them to quench more free radicals. Vitamin C itself was recently shown to be a Nrf2 activator.

ultimate protector+ nrf2 activator formula uses three modes of action

Ultimate Protector+ uses three modes of action

2 – HIGH-ORAC6.0 VALUE INGREDIENTS

By means of carefully choosing plant ingredients with the highest ORAC 6.0 values, the product can neutralize all five major types of free radicals commonly found in the body, including: 1) peroxyl, 2) hydroxyl, 3) peroxynitrite, 4) singlet oxygen, and 5) superoxide anion. Ultimate Protector+ includes many plant-based ingredients with high ORAC6.0 values. These include green tea extract, whole grape extract, curcumin, resveratrol, bilberry, and mangosteen.

Brunswick Labs tested Ultimate Protector+™using the ORAC6.0™ test. The results reveal an extremely high overall ORAC6.0 value of 272,743 µmole TE/gram (i.e., 272,743 per gram!). In addition, the results show that the formula offers excellent protection against all six types of free radicals measured. Specifically, the results show values of 3,376 µmole TE/gram for peroxyl radicals, 5,569 µmole TE/gram for hydroxyl radicals, 2,758 µmole TE/gram for peroxynitrite radicals, 221,866 µmole TE/gram for superoxide anion radicals, 34,169 µmole TE/gram for singlet oxygen radicals, and 5,005 µmole TE/gram for hypochlorite radicals. The table (below) shows for each free radical type the ORAC6.0 daily values for six capsules of Ultimate Protector+™ containing 3.55 grams of the formula.ORAC6.0 test results

The overall daily ORAC6.0™ value for six capsules obtained by adding the values for each free radical type is 968,237 units (272,743 units multiplied by 3.55 gram (serving size)! To my knowledge, no other product comes close to providing such complete protection both in terms of breadth of coverage and overall strength. For a fuller explanation of Brunswick Labs ORAC6.0™ test results for Ultimate Protector+™ please read my article “Ultimate Protector+ Brunswick Labs ORAC6.0 Test Report.”

3 – POTENT NRF2 ACTIVATORS

The science on Nrf2 activators clearly shows a wide variety of plant polyphenols act endogenously to cause genetic transcription of many protective enzymes, like superoxide dismutase, glutathione transferase, and heme oxygenase. Many well-known, well-researched Nrf2 activators are high ORAC5.0 antioxidants. These first act as antioxidants giving up an electron, and then act as weak pro-oxidants needed to stimulate Nrf2 activity. In Ultimate Protector+ these ingredients include green tea extract, whole grape extract, curcumin, resveratrol, bilberry, and mangosteen. In addition, ingredients such as extracts of apple, blueberry, cranberry, pomegranate, blueberry, apple, chokeberry, and goji berry are shown in studies to be important Nrf2 activators.

ULTIMATE PROTECTOR+ SUMMARY

Ultimate Protector+ is a powerful antioxidant and Nrf2 activator formula. Both ORAC6.0™ test results and user experience confirm its effectiveness for quenching free radicals and preventing or reducing oxidative damage from all major types of free radicals. There is currently no other antioxidant and/or Nrf2 activator formula available that provides the level of cell protection afforded by Ultimate Protector+.

Ultimate Protector+ is available from HPDI: ULTIMATE PROTECTOR+
(https://www.integratedhealth.com/antioxidants/ultimate-protector/)

12 plant-based Nrf2 activators

ULTIMATE PROTECTOR+ RESOURCES

ULTIMATE PROTECTOR+: https://www.integratedhealth.com/antioxidants/ultimate-protector/

ULTIMATE PROTECTOR ORAC6.0™ TEST RESULTS
(https://integratedhealthblog.com/wp-content/uploads/2019/08/up-orac6.pdf)

BLOG ARTICLES

Ultimate Protector+ Brunswick Labs ORAC6.0™ Test Report
https://integratedhealthblog.com/ultimate-protector-brunswick-labs-orac6-0-test-report/

Amazing Healing Potential of Natural Nrf2 Activators:
https://integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/

Preventing Free Radical Damage with Ultimate Protector+:
https://integratedhealthblog.com/amazing-healing-potential-natural-nrf2-activators/

Ultimate Protector+ Design Considerations: https://integratedhealthblog.com/scientific-basis-ultimate-protector/

Natural Phytochemical Nrf2 Activators for Chemoprevention:
https://integratedhealthblog.com/natural-phytochemical-nrf2-activators-for-chemoprevention/

New Directions For Preventing Free Radical Damage:
https://integratedhealthblog.com/new-directions-for-preventing-free-radical-damage/